Week 6 SNF Fantasy Football Preview : DET vs. KC

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  • By Nathan Hernandez

    Last Updated on October 12, 2025 9:54 am by Jon Mosales | Published: October 12, 2025

    SNF – Detroit Lions @ Kansas City Chiefs

    Point spread: DET +2.5 | KC -2.5

    Moneyline: DET +120 | KC -142

    Total: Over 52.5 | Under 52.5

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    Overview:

    Man we might be in for a treat for one of the best games of the season to date, as the Chiefs are hosting the Detroit Lions in Kansas City for Week 6’s Sunday Night Football matchup between two of the league’s juggernauts of the past few seasons. KC is fresh off a MNF loss to the Jacksonville Jaguars, and are sitting at 2-3 and currently out of the playoff picture through five weeks this season. Detroit is coming off a cruising victory over the Cincinnati Bengals in Week 5, and they’re sitting at 4-1 tied for the best record in the NFL. Despite on a slightly-shortened week, Mahomes and the Chiefs are home favorites in this game, casting a different reflection than the records of these teams might have indicated. The Chiefs have a clean bill of health on their injury report heading into this game, though, while the Lions are down a couple of key members on both sides of the football, namely CB Terrion Arnold and OT Taylor Decker.

    Quarterbacks:

    Patrick Mahomes is having a fantasy revival in 2025, and it’s happening without his top pass-catcher Rashee Rice, who is slated to rejoin the team in Week 7 after wrapping up a six-game suspension. The Lions’ defense has been beatable so far this season, and they’re ranked 28th and 32nd overall in pass rush and run stop win rates, respectively, on defense. Mahomes is the QB3 on the season and has four finishes inside the top-6 among fantasy QBs through the first five games, with at least 23 fantasy points in each of those contests. The Lions have allowed multi-touchdown passing performances in 4-of-5 games this year, and Mahomes should be able to pick apart against an injured Lions team that has a much worse pass rush than what Mahomes faced against Jacksonville on MNF. Detroit’s QB Jared Goff is a much better QB for real life than fantasy football given how heavy the Lions utilize their running game, and the lack of abilities that Goff brings to that department. He finished as the QB1 overall with a 34-point performance in Week 2, but apart from that he is averaging just 14.6 FPPG in the 4 other games and doesn’t have another top-12 finish this year. However, this feels like a game where Goff is going to need to throw more than he does 90% of the time, because they are road dogs with a Vegas point total north of 50 points.

    Running Backs:

    The Chiefs’ running back room is a frustrating one. Kareem Hunt is a slogging short-yardage touch merchant, Isiah Pacheco doesn’t get enough volume or high-value touches to be relevant, and rookie RB Brashard Smith gets high-value touches but only logged six snaps last week. In my opinion, Isiah Pacheco cannot be started because he has not received a single goal line attempt this season, while Hunt has seven on the year, and we even saw the rookie Smith get a crack at it. The Chiefs do not seem to plan on using Pacheco in that area of the field, so Kareem Hunt is subsequently a flex play because of his hold on that role, but the emergence of Brashard Smith could spell doom to Hunt’s usage in the offense, and he’s an intriguing stash for a potential post-bye rookie bump later in the season. There isn’t much to say about the two-headed monster in Detroit’s backfield. It’s a high game total for the highest-usage backfield in the league, and there should be plenty of volume for both Jahmyr Gibbs and David Montgomery to get home against KC, who is 31st in run stop win rate in the NFL so far this year.

    Wide Receivers: 


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    October 12, 2025, 9:54 am