49ers 38, Cardinals 10 (49ers covered -8, O43.5)

Postgame:  The 49ers dominated this game from start to finish on both sides of the ball.  The Cardinals were not able to get another going on offense, while on defense, they looked completely inept.  Meanwhile for the Niners, they were able to have a bunch of very strong fantasy performances this week against the lowly Cardinals defense.  With the victory, the 49ers advanced to 6-4 on the season, stealing the top spot in the NFC West from the Seahawks, who were on bye. On the other side of things, the Cardinals continue to lose key players to injury and drop to 4-7 on the year, but still have a slim hope of making the playoffs. 

Pregame: Although we have another division rivalry being featured on Monday Night Football, it is unlikely to see a crazy upset like we saw last week when the Commanders handed the Eagles their first loss of the year. The 49ers (5-4) are heavy favorites on the road, but with their bundles of talent on both sides of the ball, this shouldn’t come as a surprise. The Cardinals (4-6) will potentially be without Kyler Murray and DeAndre Hopkins on Monday, as both players are listed as questionable, but are expected to play. They also just lost Zach Ertz for the season, being placed on IR this week. There is some good news for the Cardinals though, as there is a chance to see Marquise Brown returning from IR this week. With a bunch of great fantasy options on both sides of the ball, fantasy GMs will be hopeful their studs are able to have big games and pull off a comeback in their fantasy matchups!

49ers

QB

Jimmy Garoppolo: 

Postgame: Garoppolo had his best fantasy week of the season, throwing for 228 yards and four touchdowns on 20-of-29 completions.  He has a clear path to continue his success similar to this game going forward, with the 49ers being one of the absolute best offenses in the league.  Jimmy G finished Week 11 as the QB5 and has now played his way into being a viable weekly starting option for fantasy GMs. 

Pregame: Jimmy G has played a good management style of football over the past few weeks. He is not doing anything spectacular, but the 49ers are winning games. He is a borderline starting option for fantasy GMs this week, with four teams on bye, but is more valuable in superflex leagues. Garoppolo has only cracked 300 yards once this year and has yet to throw three touchdowns in a game, so he is more of a safer option than a high-ceiling play in standard formats. The Cardinals have allowed the seventh-most fantasy points to opposing QBs this week, so he is worth a look in all leagues, if fantasy GMs have their starter on bye.

RB

Christian McCaffrey & Elijah Mitchell: 

Postgame: Mitchell and McCaffrey once again shared the rushing attempts for the 49ers on Monday night.  Mitchell finished the contest with 59 yards on nine rushes, while CMC ended with seven attempts for 39 yards. McCaffrey looked excellent in the receiving game and it seemed as if the Cardinals could not cover him, hauling in all seven targets for 67 yards. Even without scoring, he finished the week as the RB11 in PPR formats.  Once again, Mitchell did not have any usage in the passing game and seems to only be involved as an early-down back. 

Pregame: McCaffrey is the obvious preferred fantasy play of the two, but both should have a high level of involvement in this game. Last week against the Chargers, both backs saw 20 opportunities each in the win, but it was McCaffrey that played 65% of the snaps in comparison to Mitchell’s 35%. CMC has the potential to finish each week as the overall RB1, while Mitchell is in the low-end RB2 range.

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WR

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